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Literature summary extracted from
- Retinoic acid related orphan receptor alpha regulates diurnal rhythm and fasting induction of sterol 12alpha-hydroxylase in bile acid synthesis (2013), J. Biol. Chem., 288, 37154-37165.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.139 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.139 | hepatocyte | - |
Mus musculus | - |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.14.139 | CYP8B1 | - |
Mus musculus |
| 1.14.14.139 | sterol 12alpha-hydroxylase | - |
Mus musculus |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 1.14.14.139 | Mus musculus | CYP8B1 mRNA levels show a diurnal rhythm, decrease during the day and reaching the lowest levels 2 h into the dark cycle | down |
| 1.14.14.139 | Mus musculus | adenovirus-mediated gene transduction of retinoic acid-related orphan receptor alpha to mice strongly induces CYP8B1 expression (2.5fold) | up |
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Release 2023.1 (January 2023)
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